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1

Together we stand, apart we fall: how cell-to-cell contact/interplay provides resistance to ferroptosis

Vucetic, Milica, Daher, Boutaina, Cassim, Shamir, Meira, Willian, Pouyssegur, Jacques

Journal:

Cell Death and Disease

Année:

2020

Fichier:

PDF, 1.47 MB

2020

2

Independent activation of endogenous p21-activated protein kinase-3 (PAK3) and JNK by thrombin in CCL39 fibroblasts

Kenneth C. Malcolm, Jean-Claude Chambard, Dominique Grall, Jacques Pouysségur, Ellen van Obberghen-Schilling

Journal:

Journal of Cellular Physiology

Année:

2000

Langue:

english

Fichier:

PDF, 194 KB

english, 2000

3

Structure/function studies of the epithelial isoforms of the mammalian Na+/H+exchanger gene family

Ming Tse, Sue Levine, Chris Yun, Steve Brant, Laurent T. Counillon, Jacques Pouyssegur, Mark Donowitz

Journal:

Journal of Membrane Biology

Année:

1993

Langue:

english

Fichier:

PDF, 1.65 MB

english, 1993

4

A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor

Tournaire, Roselyne, Simon, Marie-Pierre, Noble, Ferdinand le, Eichmann, Anne, England, Patrick, Pouysségur, Jacques

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 229 KB

english, 2004

5

Hypoxia: the tumor's gateway to progression along the angiogenic pathway

Christiane Brahimi-Horn, Edurne Berra, Jacques Pouysségur

Journal:

Trends in Cell Biology

Année:

2001

Langue:

english

Fichier:

PDF, 2.88 MB

english, 2001

6

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

Johanna Chiche, M. Christiane Brahimi-Horn, Jacques Pouysségur

Journal:

Journal of Cellular and Molecular Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2010

7

Physical and Genetic Mapping of a Human Apical Epithelial Na+/H+ Exchanger (NHE3) Isoform to Chromosome 5p15.3

Steven R. Brant, Michael Bernstein, John J. Wasmuth, Eugene W. Taylor, John D. McPherson, Xiang Li, Susan Walker, Jacques Pouyssegur, Mark Donowitz, Chung-Ming Tse, Ethylin Wang Jabs

Journal:

Année:

1993

Fichier:

PDF, 362 KB

1993

8

Erk Kinases Link Pre-B Cell Receptor Signaling to Transcriptional Events Required for Early B Cell Expansion

Tomoharu Yasuda, Hideki Sanjo, Gilles Pagès, Yohei Kawano, Hajime Karasuyama, Jacques Pouysségur, Masato Ogata, Tomohiro Kurosaki

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2008

9

Disrupting proton dynamics and energy metabolism for cancer therapy

Parks, Scott K., Chiche, Johanna, Pouysségur, Jacques

Journal:

Nature Reviews Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 900 KB

english, 2013

10

Le stress hypoxique et nutritionnel tumoral. Nouvelles approches anticancer

Pouysségur, Jacques

Journal:

Annales de Pathologie

Année:

2010

Langue:

french

Fichier:

PDF, 175 KB

french, 2010

11

Monitoring Mitochondrial Pyruvate Carrier Activity in Real Time Using a BRET-Based Biosensor: Investigation of the Warburg Effect

Compan, Vincent, Pierredon, Sandra, Vanderperre, Benoît, Krznar, Petra, Marchiq, Ibtissam, Zamboni, Nicola, Pouyssegur, Jacques, Martinou, Jean-Claude

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2015

12

Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+symporters

Marchiq, Ibtissam, Pouysségur, Jacques

Journal:

Journal of Molecular Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2016

13

ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1

Buscà, Roser, Christen, Richard, Lovern, Matthew, Clifford, Alexander M., Yue, Jia-Xing, Goss, Greg G., Pouysségur, Jacques, Lenormand, Philippe

Journal:

BMC Evolutionary Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.77 MB

english, 2015

14

ERK2 but not ERK1 plays a key role in hepatocyte replication: An RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes

Christophe Frémin, Frédéric Ezan, Pierre Boisselier, Anne Bessard, Gilles Pagès, Jacques Pouysségur, Georges Baffet

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 932 KB

english, 2007

15

Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2

Christophe Frémin, Anne Bessard, Frédéric Ezan, Luc Gailhouste, Morgane Régeard, Jacques Le Seyec, David Gilot, Gilles Pagès, Jacques Pouysségur, Sophie Langouët, Georges Baffet

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2009

16

HIF-1α and CA IX staining in invasive breast carcinomas: Prognosis and treatment outcome

Cynthia Trastour, Emmanuel Benizri, Francette Ettore, Alain Ramaioli, Emmanuel Chamorey, Jacques Pouysségur, Edurne Berra

Journal:

International Journal of Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 464 KB

english, 2007

17

Overexpression of carbonic anhydrase XII in tissues from resectable non-small cell lung cancers is a biomarker of good prognosis

Marius I. Ilie, Véronique Hofman, Cécile Ortholan, Reda El Ammadi, Christelle Bonnetaud, Katia Havet, Nicolas Venissac, Jerôme Mouroux, Nathalie M. Mazure, Jacques Pouysségur, Paul Hofman

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 658 KB

english, 2011

18

In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH

Johanna Chiche, Yann Le Fur, Christophe Vilmen, Frédéric Frassineti, Laurent Daniel, Andrew P. Halestrap, Patrick J. Cozzone, Jacques Pouysségur, Norbert W. Lutz

Journal:

International Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2012

19

Characterization of the neuropilin-1 promoter; gene expression is mediated by the transcription factor Sp1

Mireille Rossignol, Jacques Pouysségur, Michael Klagsbrun

Journal:

Journal of Cellular Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 518 KB

english, 2003

20

Effect of mutations affecting Na+:H+ antiport activity on tumorigenic potential of hamster lung fibroblasts

Alain E. Lagarde, Arlette J. Franchi, Sonia Paris, Jacques M. Pouysségur

Journal:

Journal of Cellular Biochemistry

Année:

1988

Langue:

english

Fichier:

PDF, 715 KB

english, 1988

21

α-Thrombin-induced inositol phosphate formation in go-arrested and cycling hamster lung fibroblasts: Evidence for a protein kinase C-mediated desensitization response

Gilles L'Allemain, Sonia Paris, Isabelle Magnaldo, Jacques Pouysségur

Journal:

Journal of Cellular Physiology

Année:

1986

Langue:

english

Fichier:

PDF, 1.25 MB

english, 1986

22

TGF-β inhibits growth factor-induced DNA synthesis in hamster fibroblasts without affecting the early mitogenic events

Jean-Claude Chambard, Jacques Pouysségur

Journal:

Journal of Cellular Physiology

Année:

1988

Langue:

english

Fichier:

PDF, 749 KB

english, 1988

23

Na+/H+ antiporter gene expression increases during retinoic acid-induced granulocytic differentiation of HL60 cells

Gadiparthi N. Rao, Claude Sardet, Jacques Pouysségur, Bradford C. Berk

Journal:

Journal of Cellular Physiology

Année:

1992

Langue:

english

Fichier:

PDF, 644 KB

english, 1992

24

Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-α in human tracheal smooth muscle cells: Involvement of MAPKs, NF-κB, p300, and histone acetylation

Chiang-Wen Lee, Wei-Ning Lin, Chih-Chung Lin, Shue-Fen Luo, Jong-Shyan Wang, Jacques Pouyssegur, Chuen-Mao Yang

Journal:

Journal of Cellular Physiology

Année:

2006

Langue:

english

Fichier:

PDF, 953 KB

english, 2006

25

The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1

Marie-Pierre Simon, Roselyne Tournaire, Jacques Pouyssegur

Journal:

Journal of Cellular Physiology

Année:

2008

Langue:

english

Fichier:

PDF, 292 KB

english, 2008

26

Activation of HIF-1α in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway

Frédéric Dayan, Rebecca L. Bilton, Julie Laferrière, Eric Trottier, Danièle Roux, Jacques Pouyssegur, Nathalie. M. Mazure

Journal:

Journal of Cellular Physiology

Année:

2009

Langue:

english

Fichier:

PDF, 272 KB

english, 2009

27

Hypoxic enlarged mitochondria protect cancer cells from apoptotic stimuli

Johanna Chiche, Matthieu Rouleau, Pierre Gounon, M. Christiane Brahimi-Horn, Jacques Pouysségur, Nathalie M. Mazure

Journal:

Journal of Cellular Physiology

Année:

2010

Langue:

english

Fichier:

PDF, 467 KB

english, 2010

28

pH control mechanisms of tumor survival and growth

Scott K. Parks, Johanna Chiche, Jacques Pouyssegur

Journal:

Journal of Cellular Physiology

Année:

2011

Langue:

english

Fichier:

PDF, 153 KB

english, 2011

29

ERK1 plays a critical protective role against N-methyl-D-aspartate-induced retinal injury

Toru Nakazawa, Masahiko Shimura, Morin Ryu, Kohji Nishida, Gilles Pagès, Jacques Pouysségur, Shogo Endo

Journal:

Journal of Neuroscience Research

Année:

2008

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2008

30

Gene regulation in response to graded hypoxia: The non-redundant roles of the oxygen sensors and FIH in the HIF pathway

Frédéric Dayan, Marc Monticelli, Jacques Pouysségur, Elisabeth Pécou

Journal:

Journal of Theoretical Biology

Année:

2009

Langue:

english

Fichier:

PDF, 841 KB

english, 2009

31

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling : Delivered on 24 October 2002 at the 28th FEBS Meeting in Istanbul

Jacques Pouysségur, Philippe Lenormand

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 275 KB

english, 2003

32

Growth factor-stimulated protein synthesis is inhibited by sodium orthovanadate

Francesc Viñals, Fergus R. McKenzie, Jacques Pouysségur

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 559 KB

english, 2001

33

Système de transport du 2-céto-3-désoxy-gluconate chezE. coliK12: localisation d'un gène de structure et de son opérateur

Jacques Pouysségur, Alain Lagarde

Journal:

Molecular Genetics and Genomics

Année:

1973

Fichier:

PDF, 927 KB

1973

34

Localisation génétique de mutations 2-céto-3-désoxy-6-P-gluconate aldolase négatives chezE. coliK 12

Jacques M. Pouyssegur

Journal:

Molecular Genetics and Genomics

Année:

1971

Langue:

english

Fichier:

PDF, 706 KB

english, 1971

35

Na/H Exchange activities in NHE1-transfected OK-cells: cell polarity and regulation

Corinna Helmle-Kolb, Laurent Counillon, Danièle Roux, Jacques Pouysségur, Branka Mrkic, Heini Murer

Journal:

Pflügers Archiv European Journal of Physiology

Année:

1993

Langue:

english

Fichier:

PDF, 894 KB

english, 1993

36

Hypoxia and cancer

M. Christiane Brahimi-Horn, Johanna Chiche, Jacques Pouysségur

Journal:

Journal of Molecular Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 320 KB

english, 2007

37

A Dialogue between the Hypoxia-Inducible Factor and the Tumor Microenvironment

Frédéric Dayan, Nathalie M. Mazure, M. Christiane Brahimi-Horn, Jacques Pouysségur

Journal:

Cancer Microenvironment

Année:

2008

Langue:

english

Fichier:

PDF, 649 KB

english, 2008

38

When hypoxia signalling meets the ubiquitin-proteasomal pathway, new targets for cancer therapy

Christiane Brahimi-Horn, Jacques Pouysségur

Journal:

Critical Reviews in Oncology/Hematology

Année:

2005

Langue:

english

Fichier:

PDF, 327 KB

english, 2005

39

ERK1 and ERK2 are required for radial glial maintenance and cortical lamination

Osamu Imamura, Gilles Pagès, Jacques Pouysségur, Shogo Endo, Kunio Takishima

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2010

40

HIF-1α mediates the induction of IL-8 and VEGF expression on infection with Afa/Dr diffusely adhering E. coli and promotes EMT-like behaviour

Gaëlle Cane, Amandine Ginouvès, Sandrine Marchetti, Roser Buscà, Jacques Pouysségur, Edurne Berra, Paul Hofman, Valérie Vouret-Craviari

Journal:

Cellular Microbiology

Année:

2010

Langue:

english

Fichier:

PDF, 355 KB

english, 2010

41

Signaling Angiogenesis via p42/p44 MAP Kinase Cascade

GILLES PAGÈS, JULIE MILANINI, DARREN E. RICHARD, EDURNE BERRA, EMMANUEL GOTHIÉ, FRANCESC VIÑALS, JACQUES POUYSSÉGUR

Journal:

Annals of the New York Academy of Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 689 KB

english, 2000

42

Adenylate cyclase in a fibroblast mutant defective in glycolipid and glycoprotein synthesis

ANDERSON, WAYNE B., JAWORSKI, CYNTHIA J., GALLO, MARIA, PASTAN, IRA, POUYSSÉGUR, JACQUES

Journal:

Année:

1978

Fichier:

PDF, 203 KB

1978

43

Identification of a tetrodotoxin-sensitive Na+ channel in a variety of fibroblast lines

Pouysségur, J., Jacques, Y., Lazdunski, M.

Journal:

Année:

1980

Fichier:

PDF, 519 KB

1980

44

c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors

Blanchard, Jean-Marie, Piechaczyk, Marc, Dani, Christian, Chambard, Jean-Claude, Franchi, Arlette, Pouyssegur, Jacques, Jeanteur, Philippe

Journal:

Année:

1985

Fichier:

PDF, 393 KB

1985

45

Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin

Chambard, Jean Claude, Paris, Sonia, L'Allemain, Gilles, Pouysségur, Jacques

Journal:

Année:

1987

Fichier:

PDF, 518 KB

1987

46

Mutant α subunits of Gi2 inhibit cyclic AMP accumulation

Wong, Yung H., Federman, Alex, Pace, Ann M., Zachary, Ian, Evans, Tony, Pouysségur, Jacques, Bourne, Henry R.

Journal:

Année:

1991

Fichier:

PDF, 376 KB

1991

47

A functional role for the p62–ERK1 axis in the control of energy homeostasis and adipogenesis

Lee, Sang Jun, Pfluger, Paul T, Kim, Ji Young, Nogueiras, Ruben, Duran, Angeles, Pagès, Gilles, Pouysségur, Jacques, Tschöp, Matthias H, Diaz-Meco, Maria T, Moscat, Jorge

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 887 KB

english, 2010

48

Regulation of the Na+/H+ exchanger isoform NHE1: Role of phosphorylation

Bianchini, Laurence, Pouysségur, Jacques

Journal:

Kidney International

Année:

1996

Langue:

english

Fichier:

PDF, 420 KB

english, 1996

49

The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling

Berra, Edurne, Ginouvès, Amandine, Pouysségur, Jacques

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 222 KB

english, 2006

50

Cyclin D1 expression is a major target of the cAMP-induced inhibition of cell cycle entry in fibroblasts

L'Allemain, Gilles, Lavoie, Josée N, Rivard, Nathalie, Baldin, Véronique, Pouyssegur, Jacques

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 627 KB

english, 1997